Turkish Journal of Geriatrics 2017 , Vol 20, Issue 4
RELATIONSHIP BETWEEN SEVERITY OF OBSTRUCTIVE SLEEP APNEA AND AGE AND INFLAMMATORY MEDIATORS IN GERIATRIC PATIENTS
Birgül TUHANIOĞLU1, Sanem Okşan ERKAN1, Zehra DINIZ2, Orhan GÖRGÜLÜ1, Gökhan KURAN1
1Adana Numune Research and Training Hospital, Otolaryngology Clinic ADANA
2Adana Ceyhan State Hospital, Chest Diseases Clinic ADANA
Introduction: There is a high prevalence of obstructive sleep apnea in the age group of ≥65 years. The neutrophil-lymphocyte ratio (NLR) and mean platelet volume (MPV) are used as systemic inflammatory markers. In this study, it was aimed to investigate the association between polysomnography data and inflammatory mediators as well as the association between age and severity of obstructive sleep apnea in patients ≥ 65 years.

Metarials and Method: This study included 154 patients with obstructive sleep apnea symptoms. Patients were divided into two groups: patients ≥65 years (study group) and those<65 years (control group). Polysomnography was performed in all patients. Neutrophil levels, lymphocyte counts, mean platelet volume and other hematological parameters were analyzed.

Results: There was no statistically significant difference between age groups in terms of body mass index (BMI), apnea-hypopnea index (AHI) and inflammatory mediator values (p>0.05). The severity of obstructive sleep apnea was not significantly different between patients in both groups (p>0.05). Mean platelet volume of patients with moderate apneahypopnea index in both groups was found to be significantly lower than that of those with severe apnea-hypopnea index (p<0.05).

Conclusion: According to the study results, the severity of obstructive sleep apnea and inflammatory mediator did not correlate with age. Keywords : Sleep apnea syndrome; Geriatrics; Polysomnography