Turkish Journal of Geriatrics 1998 , Vol 1, Issue 1
Lipid Profile in Stroke as a Risk Factor and Clinical Correlation
Turali ERASLAN, Şerefnur ÖZTÜRK, İsmet MELEK, Taşkın DUMAN, Şenay ÖZBAKIR
Ankara Numune Hastanesi Nöroloji Kliniği-ANKARA Lipid profile in stroke has been evaluated in different studies which included apolipoproteins and which did not include and lipids and lipoproteins has been suggested as major risk factors in various stroke types and subgroups. It has been stressed for the importance of to know lipid and lipid profile of different populations because of influence of race, gender, age and environmental factors on lipid profile. This study was planned to compare lipid and lipoprotein profile of stroke patients with lipid profile of controls whose had similar risk factors, and reflection of lipid profile to clinical features. Lipid and lipoprotein values of 176 acute stroke patients who admitted to our department, compared with values of 71 control subjects who had similar risk factors. There was not significant difference between the mean age of 176 stroke patients (62.67±10.85) and the mean age of controls (60.42±7.01) (p=0.114). Apo A-1 and HDL -C levels were not different in stroke patients than in controls (p=0.008) whereas total cholesterol (p=0.000), LDL-C (p=0.001), VLDL-C (p=0.008) and triglycerid (p=0.019) were higher than controls. In the evaluation of for Toronto Stroke Scale scores of the patients and Apo A-1 and Apo B values, there was a significant positive correlation between Apo B and Toronto Stroke Scale scores (p=0.003). No correlation was found for Apo A-1. Beside the different lipid and lipoprotein profile in stroke patients and controls, correlation of increased Apo B and and Toronto Stroke Scale can suggest reflection of increased Apo B ON clinical profile with a strong relation. Keywords : Apolipoprotein A-1, Apolipoprotein B, Cholesterol, Hemorrhagic Stroke, Ischemic Stroke, Lipid