Turkish Journal of Geriatrics 2014 , Vol 17, Issue 2
EVALUATION OF POTENTIALLY INAPPROPRIATE DRUG USE AND MEDICAL NON-ADHERENCE IN A COMMUNITY-DWELLING ELDERLY POPULATION: A CROSS-SECTIONAL STUDY
Yonca SÖNMEZ1, Halil AŞCI2, Gülşen OLGUN İZMİRLİ3, Duru GÜNDOĞAR4, Fatma Nihan CANKARA2, Şükriye YEŞİLOT2
1Süleyman Demirel Üniversitesi Tıp Fakültesi, Halk Sağlığı Anabilim Dalı ISPARTA
2Süleyman Demirel Üniversitesi Tıp Fakültesi, Farmakoloji Anabilim Dalı ISPARTA
3Gönen Toplum Sağlığı Merkezi ISPARTA
4Süleyman Demirel Üniversitesi Tıp Fakültesi, Psikiyatri Anabilim Dalı ISPARTA
Introduction: The objectives of the study were to evaluate potentially inappropriate drug use and medical non-adherence and to determine the risk factors for potentially inappropriate drug use and medical non-adherence in the elderly dwelling in a community health center service area.

Materials and Method: The cross-sectional study included all individuals aged 65 years and older (n=687) dwelling in the area of a community health center in Isparta, Turkey. The dependent variables of the study were potentially inappropriate drug use and medical non-adherence. The structured questionnaire, comprising both dependent and independent variables, was administered to elderly people by conducting face-to-face interviews at home. Chi-square, independent samples t-test, and logistic regression were used for data analysis.

Results: Among the elderly using at least one drug per day, 17.6% were using at least one potentially inappropriate medication. Non-steroidal anti-inflammatory drugs and digoxin (in doses >0.125 mg/day) were the most common drugs that were used inappropriately. Medical non-adherence was determined in 40.6% of the elderly. The most common non-adherent behavior was "forgetting to take the medication." In the multivariate analysis, polymorbidity (p=0.001) and polypharmacy (p=0.016) were risk factors for potentially inappropriate drug use. The only risk factor for medical non-adherence was "not knowing most of the side effects of the drug" (p=0.018).

Conclusion: In this study, lower prevalence rates than those for most previous studies were found for both potentially inappropriate drug use and medical non-adherence. Since polymorbidity and polypharmacy were risk factors for potentially inappropriate drug use, physicians should be cautious in the selection of drugs for elderly patients with polymorbidity. Keywords : Aged, Inappropriate Prescribing; Medication Adherence