Turkish Journal of
GERIATRICS

Materials and Method: The retrospective study reviewed 1981 patients aged 65?104 years who were bedridden and followed at University of Health Sciences, Antalya Training and Research Hospital Family Medicine Clinic from 2016 to 2018. Due to the effects on studied test parameters, patients with anemia were excluded from the study, and 898 patients included. The baseline variables red cell distribution width, mean platelet volume, platelet-to-lymphocyte ratio, and neutrophil-tolymphocyte ratio were compared between survivors and non-survivors.

Results: Of the 898 patients, 141 (15.7%) died during follow-up. Mean red cell distribution width (15.7%), platelet-to-lymphocyte ratio (140.5), and neutrophilto- lymphocyte ratio (3.14) levels in non-survivors were statistically significantly higher than those of survivors (14.9%, p<0.001; 125, p=0.030; and 2.38, p<0.001, respectively). The retrospective follow-up revealed that red cell distribution width, platelet-to-lymphocyte ratio and neutrophil-to-lymphocyte ratio levels (17.6%, 205.82, and 4.99, respectively) had increased during the last three months before death, but this was not statistically significant. The results of univariate logistic regression analyses showed that mortality was positively associated with red cell distribution width and neutrophil-to-lymphocyte ratio. In a multivariate model, red cell distribution width was identified as an independent predictive factor associated with mortality.

Conclusion: Red cell distribution width, platelet-to-lymphocyte ratio, and neutrophil-to-lymphocyte ratio may be strong predictors of mortality in patients who have become bedridden, and alarms to take action for measures. Keywords : Erythrocytes; Neutrophils; Lymphocytes; Blood Platelets; Mortality; Aged