2University of Health Sciences, Gulhane Medical Faculty, Geriatric Medicine, Ankara, Turkey
3University of Health Sciences, Gulhane Medical Faculty, Radiology, Ankara, Turkey
4University of Health Sciences, Gulhane Medical Faculty, Infectious Diseases and Clinical Microbiology, Ankara, Turkey
5University of Health Sciences, Gulhane Medical Faculty, Intensive Care Medicine, Ankara, Turkey
6University of Health Sciences, Gulhane Medical Faculty, Emergency Medicine, Ankara, Turkey
7University of Health Sciences, Gulhane Medical Faculty, Medical Informatics, Ankara, Turkey
8University of Health Sciences, Gulhane Medical Faculty, Anesthesiology and Reanimation, Ankara, Turkey DOI : 10.31086/tjgeri.2020.181 Ä°ntroduction: COVID-19 infection may be atypically presented in the older adults with a poor prognosis. In this study, we aimed to investigate the clinical and laboratory differences of COVID-19 course in older patients.
Materials and Method: The demographic, clinical, laboratory and radiological data of the patients hospitalized with COVID-19 infection were compiled retrospectively. A randomized control group was created from younger patients. Chest tomography of the patients were examined and scored.
Results: Data of 100 older and 127 younger patients with COVID-19 infection, and 80 non-COVID older patients were evaluated retrospectively. While the mean CRP, fibrinogen, procalcitonin, urea, LDH, INR, PT, Troponin-I, CK-MB and total radiological lung score were significantly higher in older patients; the mean hemoglobin, hematocrit and d-dimer were significantly higher in younger patients. Lymphopenia was more common and the mortality rate was higher in the older adults. Lymphopenia, presence of comorbidity, being over the age of 75, and radiological lung involvement were identified as mortality risk factors in older patients. The cut-off values for mortality were as follows; age?77 years, lymphocyte#? 700x103 cells/?L, CRP?108.71 mg/L, d-dimer?2.25 mg/L, fibrinogen?383 mg/L, INR?1.05, PT ?12.5 seconds, aPTT?31 seconds, Troponin-I?19.1 pg/mL, total lung score?6 points. COVID-19 did not increase mortality much more than other hospital-requiring clinical events in older adults (17% vs 26.25%).
Conclusion: The older adults require special attention in COVID-19 pandemic. Those with comorbidities, lymphopenia, high d-dimer levels, and extensive lung involvement in the initial tomography should be followed-up closely.
Keywords : Covıd-19; Aged; Geriatrics; Mortality; Radiology