Turkish Journal of Geriatrics 2021 , Vol 24, Issue 3
RELATIONSHIP BETWEEN THE PROGNOSTIC NUTRITIONAL INDEX AND ALL-CAUSE MORTALITY IN ELDERLY PATIENTS WITH NON-ST SEGMENT ELEVATION MYOCARDIAL INFARCTION
Özge Çakmak KARAASLAN1, Cem ÇÖTELİ1, Hasan Can KÖNTE2, Murat Oğuz ÖZİLHAN1, Orhan MADEN1
1Ankara City Hospital, Department of Cardiology, Ankara, Turkey
2Kahramankazan State Hospital, Department of Cardiology, Ankara, Turkey
DOI : 10.31086/tjgeri.2021.234 Background: Patients over 65 years of age with non-ST segment elevation myocardial infarction are at higher risk of mortality and morbidity than younger patients. The prognostic nutritional index is a combined immunologicalnutritional status score based on serum albumin levels and lymphocyte values. We evaluated the association between prognostic nutritional index value and all-cause mortality in elderly patients with non-ST segment elevation myocardial infarction. The current study presents the first evaluation of prognostic nutritional index in elderly patients with non-ST segment elevation myocardial infarction.

Methods: This was a retrospective observational study. The study population was divided into two groups according to their admission prognostic nutritional index. A prognostic nutritional index of 46 was determined as the optimal cutoff value to predict the primary endpoint, which was all-cause death during the follow-up period.

Results: Compared to patients with a prognostic nutritional index ? 46, those with a prognostic nutritional index < 46 were older (p < 0.001) and more often had a history of hypertension and known coronary artery disease (p = 0.001). All-cause mortality was significantly higher in the group with lower prognostic nutritional index (12.5% vs 4.8%; p = 0.007). The prognostic nutritional index predicted the primary endpoint, and this prediction was statistically significant (sensitivity 71%; specificity 67%). Univariate Cox regression analyses and multivariate Cox regression analyses showed that a cut-off level of prognostic nutritional index < 46 was significantly associated with the primary endpoint.

Conclusions: The prognostic nutritional index score was associated with all-cause mortality in elderly patients. Keywords : Mortality; Non-ST Elevated Myocardial Infarction; Nutrition Assessment