Turkish Journal of Geriatrics
2022 , Vol 25, Issue 2
THE "SUNSHINE" VITAMIN (D) IN OLDER ADULTS: BEYOND BONE HEALTH
1Karin Grech Hospital, Pieta, Malta, Geriatric medicine department, Pieta, Malta
DOI :
10.31086/tjgeri.2022.291
Vitamin D deficiency is reaching alarming levels worldwide and it is
highly prevalent in older adults. The association of vitamin D deficiency and
osteoporosis has been well studied but in the last decade numerous studies
have been exploring the efficacy of treating vitamin D deficiency in order to
prevent or treat other common conditions found in the older population.
There is robust evidence that vitamin D supplementation together with
calcium prevents fracture risk, but there is equivocal evidence with regards
to falls reduction. There is no substantial evidence that it decreases frailty,
sarcopenia, cognitive impairment, depression and the risk of cardiovascular
or diabetes. Research is showing that vitamin D supplementation may
prevent acute respiratory tract infections and COPD exacerbations and it
might also decrease cancer mortality. Screening for vitamin D deficiency is
recommended in all older adults with musculoskeletal diseases and in COPD
patients hospitalised with an exacerbation. There is still controversial evidence
for the optimal recommended supplementation dose, but most guidelines
recommend around 800 IU of vitamin D daily as a maintenance dose for bone
health. Despite the established benefits that vitamin D has on musculoskeletal
health, it is still unclear if sufficient vitamin D and vitamin D supplementation
will benefit the other common conditions. Therefore, future well-designed
randomised controlled studies are still needed.
Keywords :
Vitamin D; older adults; osteoporosis; frailty; sarcopenia; COPD