2Prof.Dr.Cemil Taşcıoğlu City Hospital, Clinic of Internal Medicine, İstanbul, Turkey DOI : 10.31086/tjgeri.2022.313 Introduction: In this study, we aimed to investigate the prognostic effects of platelet-to-lymphocyte ratio biomarker in the group of laboratory-confirmed Coronavirus Disease-19 (COVID-19) geriatric patients and compare them with the group of patients under 75 years of age.
Material and methods: The platelet-to-lymphocyte ratio were recorded for oxidative stress response when it is decided to transfer patients from the emergency room COVID-19/area to the COVID-19 /service, at the time of admission to intensive care unit due to arterial oxygen partial pressure (PaO2 mmHg) to fractional inspired oxygen (FiO2) < 200 mmHg, at the time of discharge from intensive care unit and exitus.
Results: It was found that the mean age of the survivors was significantly lower than those who had died (p = 0,016). In Post-hoc analysis, the plateletto- lymphocyte ratio values at hospitalization of ? 75years old patients who had died were found to be significantly different compared to patients 75 < years (p = 0.006)who were survived and patients 75 ? years who had died (p = 0.043). Only hospitalization platelet-to-lymphocyte ratio value and age data were found to be associated with mortality. According to mortality;the cut-off value for platelet-to-lymphocyte ratio at the time of admission to the COVID-19/ service in patients 75 ? years at the time of admission to ICU in patients 75 < years was determined as 411.15 and 216.54, respectively.
Conclusion: The clinical use of the platelet-to-lymphocyte ratio may be a suitable marker in geriatric patients for determining disease severity and can be used as a predictive factor for determining the poor prognosis.
Keywords : Aged; Platelet Count; Lymphocytes; COVID-19