Turkish Journal of Geriatrics
2010 , Vol 13 (Supplement)
ALOIS ALZHEIMER and ALZHEIMER'S DISEASE
Hacettepe Üniversitesi Tıp Fakültesi Nöroloji Anabilim Dalı Emekli Öğretim Üyesi Ankara
“Alois” Alzheimer (14 June 1864 – 19 December 1915) was a German
psychiatrist and neuropathologist. Alzheimer is credited with identifying the first
published case of “presenile dementia”, which Kraepelin would later identify as
Alzheimer's disease. Alois Alzheimer observed a patient at the Frankfurt named
Auguste D (Deter). The 51-year-old patient had strange behavioral symptoms,
including a loss of short-term memory. In April 1906, Deter died and Alzheimer
had the patient records and the brain brought to Munich where he was working
at Kraepelin's lab. He would use the staining techniques to identify amyloid
plaques and neurofibrillary tangles. A speech given on November 1906 was
the first time the pathology and the clinical symptoms of the disease were presented
together. Alzheimer's disease destroys brain cells, causing memory loss
and problems with thinking and behavior severe enough to affect work, lifelong
hobbies or social life. Is the most common form of dementia. Alzheimer's disease
accounts for 50 to 80 percent of dementia cases. Has no current cure.
Keywords :
Alzheimer Disease/history; History, 19th Century; History, 20th Century; Neurology/history