2Dokuz Eylül Üniversitesi Tıp Fakültesi Kalp ve Damar Cerrahisi Anabilim Dalı İZMİR
3Dicle Üniversitesi Tıp Fakültesi Fizik Tedavi ve Rehabilitasyon Anabilim Dalı DİYARBAKIR
4Gazi Magusa Devlet Hastanesi Fizik Tedavi ve Rehabilitasyon KliniÄŸi, GAZÄ° MAGUSA/KKTC
5Dokuz Eylül Üniversitesi Tıp Fakültesi Radyoloji Anabilim Dalı İZMİR
6Dokuz Eylül Üniversitesi Tıp Fakültesi Halk Sağlığı Anabilim Dalı İZMİR Introduction: The aim of the present study is to investigate the factors,affecting osteoporosis and subclinical vertebral fracture in patients with peripheral arterial disease(PAD).
Materials and Method: Eighty patients over 45 years of age with a diagnosis of PAD and without a history of osteoporosis were included in the study.The patients were queried in terms of demographic characteristics,calcium intake and physical activity.BMD was measured by a dual energy X-ray absorbsiometer(DEXA).The loss of vertebral height was determined.PAD was staged according to Fontaine's classification.Serum calcium,phosphorus,alkaline phosphatase, 25(OH)D,parathormone,homocysteine and B12 levels were measured and thyroid,renal and hepatic function tests were performed.
Results: According to the DEXA measurements,19.17% (14)of the patients had osteoporosis while 63.01%(46) of them had osteopenia.Of the patients 28(36.70%)and 8(10.12%)had grade 1 and grade 2 vertebral fractures, respectively.Radiologically confirmed vertebral fractures were not present in 43(53.2%) patients.No significant relation was found between the stage of the PAD, BMD and t scores (p>0.05). On the other hand,subclinical vertebral fractures significantly correlated with the stage of the disease and the weakness symptom(p<0.05).
Conclusion: The stage of the disease showed no correlation with osteoporosis,but correlated with the grade of subclinical vertebral fracture.Thus, this group of patients should be investigated for osteoporosis and evaluated both with BMD measurement and direct radiography.
Keywords : Peripheral Arterial Disease; Osteoporosis; Fractures, Compression