Turkish Journal of
GERIATRICS

¹Adnan Menderes Ãœniversitesi Tıp Fakültesi İç Hastalıkları Anabilim Dalı, AYDIN
²Adnan Menderes Ãœniversitesi Tıp Fakültesi İç Hastalıkları Anabilim Dalı Hematoloji Bilim Dalı, AYDIN
³Adnan Menderes Ãœniversitesi Tıp Fakültesi İç Hastalıkları Anabilim Dalı Gastroenteroloji Bilim Dalı, AYDIN Heyde syndrome was first described by Edward Heyde in 1958 in ten patients with calcific aortic stenosis and gastrointestinal hemorrhage. This syndrome is characterized by calcific aortic stenosis, acquired von Willebrand disease, and angiodysplasia in colon and caecum causing gastrointestinal hemorrhage. A 71 years old male was admitted to our clinic, because of fatigue, melena, and hematochezia. On medical history, there was an aortic valve replacement due to aortic stenosis six months ago and gastrointestinal hemorrhage three months ago. After colonoscopic examination, multiple angiodysplasia was detected at sigmoid colon. The level of von Willebrand factor was low. The patient was diagnosed as Heyde syndrom. Heyde syndrome should be considered in patients with von Willebrand disease, aortic valve replacement and gastrointestinal hemorrhage due to intestinal angiodysplasia. Keywords : Heyde Syndrome, Gastroinestinal Hemorrhage, Angiodysplasia, von Willebrand Disease