2Prof. Dr. Cemil Tascioglu City Hospital, Nephrology, Istanbul, Turkey DOI : 10.29400/tjgeri.2023.366 Introduction: A link exists between inflammation and left ventricular hypertrophy, which is a risk factor for cardiovascular disease in patients with end-stage renal failure. Neutrophil, lymphocyte, and platelet counts are used to calculate the systemic immune inflammation index. To calculate the neutrophil to albumin ratio, we divided the total number of neutrophils by the albumin concentration. Some articles have illustrated the value of systemic immune inflammation index and neutrophil to albumin ratio for diagnosing disorders associated with inflammation. The purpose of this study was to investigate whether a connection exists between left ventricular hypertrophy and inflammation, as measured by systemic immune inflammation index and neutrophil to albumin ratio, in hemodialysis patients aged >65 years.
Materials and Method: This study included 51 patients who had been receiving HD for at least three months. Test results and echocardiography measurements were obtained from patient files.
Results: Average patient age was 72.88±5.12 years. Patients were divided into two groups based on left ventricular hypertrophy status. C reactive protein, systemic immune inflammation index and neutrophil to albumin ratio were considerably lower in the left ventricular hypertrophy (-) group, and multivariate logistic regression analysis revealed that high neutrophil to albumin ratio was an independent predictor of left ventricular hypertrophy (odds ratio [OR]:8.83, 95 percent confidence interval [CI]:1.32-28.83, P .0005), in conjunction with a high C reactive protein level (OR:3.45, 95 percent CI:1.905-6.645, P .005).
Conclusion: Neutrophil to albumin ratio correlates with C-reactive protein and left ventricular hypertrophy, thereby predicting the inflammation characteristic of left ventricular hypertrophy.
Keywords : Inflammation; Hypertrophy, Left Ventricular; Renal Dialysis