Turkish Journal of Geriatrics 2014 , Vol 17, Issue 1
THE EFFECT OF THE VITAMIN D DEFICIENCY ON THE HYPOCALCAEMIA AFTER THYROIDECTOMY IN GERIATRIC PATIENTS
Ali Levent IŞIK, Serkan TEKSÖZ, Akif Enes ARIKAN, Osman Baran TORTUM, Murat ÖZCAN, Yusuf BÜKEY, Ateş ÖZYEĞİN
İstanbul Üniversitesi Tıp Fakültesi Genel Cerrahi Anabilim Dalı İSTANBUL Introduction: Post-thyroidectomy hypocalcaemia is common and depends on many factors. Vitamin D has critical role in calcium homeostasis. The main purpose of this study was to determine the effect of vitamin D deficiency on hypocalcaemia after thyroidectomy in geriatric patients.

Materials and Method: The study involved 259 patients who had received a total thyroidectomy at Istanbul University, Cerrahpaşa Medical Faculty, Department of General Surgery between 2012 and 2013. Patients' demographics, preliminary diagnosis, preoperative serum Vitamin- D, PTH, calcium, phosphorus, albumin, ALP, fT3, fT4, TSH and postoperative PTH, and calcium levels were recorded prospectively and examined retrospectively. Patients were separated into two groups: 65 years old and over (Group 1) and under 65 (Group 2).

Results: There were 49 patients in Group 1 and 210 patients in Group 2. In total 189 were female (73%) and 70 were male (27%). In 22 Group1 patients and 102 Group 2 patients, the serum vitamin D value was <15ng/ml. Mean vitamin D(g/dl) was 8.08±2.9, preoperative PTH(pg/ml) was 83.92±41.7, postoperative PTH(pg/ml) was 60.22±42.9, and postoperative calcium( mg/dl) was 8.57±0.58 for the 22 Group 1 patients and 8.58±3.2, 62.11±21.5, 38.97±32.3, and 8.45±0.67 for the 102 Group 2 patients, respectively. The only significant difference was for preoperative PTH (p=0.026).

Conclusion: These results show that, even though vitamin D deficiency is common in geriatric patients, it does not have a significantly different effect on post-thyroidectomy hypocalcaemia in geriatric patients than in non-geriatric patients. Keywords : Hypocalcaemia; Thyroidectomy; Vitamin D Deficiency; Geriatrics; Parathyroid Hormone