Turkish Journal of Geriatrics
2010 , Vol 13 (Supplement)
HYPERLIPIDEMA IN OLDER PATIENTS AND METHODS OF TREATMENT METHODS
Karadeniz Teknik Üniversitesi Tıp Fakültesi Kardiyoloji Anabilim Dalı, TRABZON
Old population in the world gradually increases. With aging, cardiovascular
(CV) diseases are more frequent. Atherosclerosis is the most important
pathologic event among CV diseases. Hyperlipidemia is one of the most important
risk factor for developing atherosclerosis. It was shown that risk for developing
CV diseases is reduced with lipid lowering treatments. Hyperlipidemia
therapy is also beneficial in older people as well as in young ones. However,
older people have more distinct characteristics than old people have. Physiologic
variables in lipid profiles may occur with getting older. Recent randomized
controlled trials shown that lipid lowering therapies have beneficial effects on
older people, although previous studies did not enrolled old people. In current
guidelines, lipid lowering therapies are recommended for prevention and treatment
of CV diseases whithout taking age edge into account. However, there
are some deliberate concerns about the safey of lipid-lowering agents. According
to studies, drug therapy administration up to 75 years seems to be safe
and beneficial. Prospective, randomized clinical trials enrolling older peoole
more than 80 years-old and big sample size are needed to be conducted in
recent days.
Keywords :
Aged; Hyperlipidemia