Turkish Journal of Geriatrics 2018 , Vol 21, Issue 2
PREDICTING MORTALITY AND MORBIDITY OF GERIATRIC FEMORAL FRACTURES USING A MODIFIED FRAILTY INDEX AND PERIOPERATIVE FEATURES: A PROSPECTIVE, MULTICENTRE AND OBSERVATIONAL STUDY
Fatma SARICAOĞLU1, Şemsi Mustafa AKSOY2, Aysun YILMAZLAR3, Derya ÖZKAN4, Elif ÇOPUROĞLU5, Eser Özlem ÜNLÜSOY6, Perihan EKMEKCİ7, Mehmet Anıl SÜZER8, Güldeniz ARGUN9, Hasibe SUNUL10, İsmail DEMİREL11, Ahmet EROĞLU12, Filiz Solmaz ALKAYA13, Deniz YÜCE14, Mutlu HAYRAN15
1Hacettepe University, Faculty of Medicine, Department of Anesthesiology and Reanimation, Ankara, Turkey
2Ankara Yıldırım Beyazıt University, Faculty of Medicine, Department of Anesthesiology and Reanimation, Turkey
3Private Medicabil Hospital, Anesthesiology and Reanimation, Bursa, Turkey
4University of Health Sciences, Dışkapı Yıldırım Beyazıt Training and Research Hospital, Department of Anesthesiology and Reanimation, Ankara, Turkey
5Trakya University, Faculty of Medicine, Department of Anesthesiology and Reanimation, Edirne, Turkey
6Ä°stanbul University, CerrahpaÅŸa Faculty of Medicine, Department of Anesthesiology and Reanimation, Ä°stanbul, Turkey
7Ufuk University, Rıdvan Ege Hospital, Department of Anesthesiology and Reanimation, Ankara, Turkey
8Cankaya Hospital, Anesthesiology and Reanimation, Ankara, Turkey
9Dr Abdurrahman Yurtaslan Ankara Onkology Training and Research Hospital, Department of Anesthesiology and Reanimation, Ankara, Turkey
10University of Health Sciences, Haseki Training and Research Hospital, Department of Anesthesiology and Reanimation, Ä°stanbul, Turkey
11Fırat University, Faculty of Medicine, Department of Anesthesiology and Reanimation, Elazığ, Turkey
12Karadeniz Technical University, Faculty of Medicine, Department of Anesthesiology and Reanimation, Trabzon, Turkey
13Süleyman Demirel University, Faculty of Medicine, Department of Anesthesiology and Reanimation, Isparta, Turkey
14Hacettepe University, Cancer Institute, Department of Preventive Oncology, Ankara, Turkey
15Hacettepe University, Cancer Institute, Department of Preventive Oncology, Ankara, Turkey
DOI : 10.31086/tjgeri.2018240413 Introduction: Femoral fracture is associated with high geriatric mortality. Frailty is the increased vulnerability to stressors resulting from aging-associated decreases in physiological reserve. We aimed to predict 30-365-day postoperative mortality and morbidity rates using modified frailty index and perioperative characteristics in geriatric femoral fractures.

Materials and Method: Using a prospective observational design, data were collected from patients >65 years undergoing femoral fracture surgery from 13 different hospitals in 2016 and 2017. Post-discharge follow-up periods were 30, 90, 180, and 365 days. Age, sex, modified frailty index and anaesthesia types used during surgery were recorded. Renal markers, troponin I and haemoglobin levels were examined preoperatively and postoperatively at 24 and 72 hours.

Results: We included 392 patients in this study. The age of the patients were between 65 and 101 (mean, 79±11.9). Median modified frailty index was 5 (interquartile range, 2?7). Increase in modified frailty index increased mortality rate. Mortality rate at postoperative 30 days was 9.8%, while overall study mortality rate was 23%. Spinal anaesthesia was administered in 205 patients (52.3%, most frequent), followed by general in 110 (28.1%), peripheral nerve blocks in 21 (5.4) and spinal-epidural in 43 (11%). Anaesthesia type affected both intensive care unit (p<0.001) and total hospitalization (p<0.012) duration. A logistic regression model revealed that frailty index, preoperative creatinine and centre type were independent mortality predictors.

Conclusion: Increased modified frailty index was associated with higher postoperative mortality risk, thus providing an additional way for improving risk stratification. Preoperative creatinine increase and centre types are determining factors in mortality. Keywords : Frail elderly; Geriatrics; Femoral fractures; Anesthesia; Mortality; Morbidity