Turkish Journal of Geriatrics
2010 , Vol 13, Issue 1
URINARY INCONTINENCE IN THE ELDERLY AND ITS PHARMACOLOGICAL TREATMENT
Hacettepe Üniversitesi Tıp Fakültesi Üroloji Anabilim Dalı ANKARA
Urinary incontinence, which may lead serious psychological and social complications such as
depression, anxiety, embarrassment, and social isolation is an important and common health
care problem affecting the elderly population. Successful management of urinary incontinence in
this population requires an understanding of the anatomical and physiological changes due to
the aging process. Different therapeutic modalities often lead to an appreciable improvement of
the symptoms, and sometimes a cure even in old patients. Pharmacologic therapy may be an
option, however when selecting a drug therapy for the management of an elderly patient, in
addition to considering evidence of clinical efficacy and tolerability, issues of safety specific to this
age group should be borne in mind. Anticholinergic agents are important in the treatment of urinary
incontinence. Each has demonstrated efficacy for the treatment however, their pharmacokinetic
and adverse event profiles differ somewhat due to structural differences, muscarinic
receptor subtype selectivities, and organ selectivities.
Keywords :
Urinary incontinence; Elderly; Pharmacotherapy; Anticholinergics