Turkish Journal of Geriatrics 2015 , Vol 18, Issue 3
CONJUNCTIVITIS AS A RARE SIDE-EFFECT OF RISEDRONATE: A CASE REPORT
Gülcan ÖZTÜRK1, Ece AYDOĞ2, Duygu GELER KÜLCÜ3
1Gebze Fatih State Hospital, Physical and Rehabilitation Clinic, KOCAELİ
2Yeditepe University, Physical and Rehabilitation Clinic, İSTANBUL
3Haydarpaşa Numune Training and Research Hospital, Physical and Rehabilitation Clinic, İSTANBUL
Osteoporosis is common metabolic bone disease in older people. Bisphosphonates is usually used in the management of osteoporosis. However, a small number of patients have been recognized to develop ocular inflammation due to administration of bisphosphonates. We report the case of risedronate-induced conjunctivitis in a 68-year-old woman. This was successfully treated with stopping risedronate. Applying Naranjo's adverse drug reaction probability scale, a causality assessment was made which categorized this reaction as probable with a score of 7. This case report reviews the literature on the ocular effects of risedronate and discusses a possible mechanism for the association. Although ocular adverse effects of bisphosphonates are rare, it may effect eyesight. Physical Medicine and Rehabilitation clinicians should be aware of ocular side- effects in older patients because a delay in diagnosis may result in serious adverse outcomes. Keywords : Aged; Osteoporosis; Risedronate; Conjunctivitis