Turkish Journal of Geriatrics 2015 , Vol 18, Issue 2
A CASE OF PYODERMA VEGETANS ASSOCIATED WITH CROHN’S DISEASE SHOWING GOOD RESPONSE TO PREDNISOLONE
Ahu YORULMAZ1, Başak YALÇIN1, İrem GENÇ1, Ferda ARTUZ1, Servet GÜREŞCİ2
1Ankara Numune Training and Research Hospital Dermatology, ANKARA
2Ankara Numune Training and Research Hospital Pathology, ANKARA
Pyoderma vegetans, also known as pyodermatitis vegetans, is a rare inflammatory dermatosis characterized by vesiculopustular lesions and vegetating plaques most commonly affecting the scalp, trunk, flexural areas and extremities. The etiopathogenesis of pyoderma vegetans has not been clearly elucidated yet; however, it has been proposed that pyoderma vegetans is associated with a number of underlying conditions, including ulcerative colitis, cutaneous T-cell lymphoma primary immunodeficiency, alcoholism and human immunodeficiency virus infection. Although pyoderma vegetans may also be seen in healthy individuals, considerable association between immunosuppression and pyoderma vegetans is evident. Moreover, the occurrence of pyoderma vegetans and its oromucosal analogue, pyostomatitis vegetans, has been reported to be as high as 75% in patients with inflammatory bowel disease; hence, pyoderma vegetans has been considered to be an indicator of inflammatory bowel disease. On the other hand, the association of pyoderma vegetans with Crohn’s disease has been rarely documented, and most of the reported cases are associated with ulcerative colitis. Here, we present a case of pyoderma vegetans associated with Crohn’s disease that showed remarkable response to corticosteroid therapy. Keywords : Pyoderma; Crohn Disease; Inflammatory Bowel Disease; Corticosteroids