Turkish Journal of Geriatrics 2013 , Vol 16, Issue 1
COMPARISON OF TRACE ELEMENT LEVELS BETWEEN AGED T1 STAGE BLADDER CANCER PATIENTS AND NORMAL DONORS USING THE ICP/MS METHOD
Yasemin BENDERLİ CİHAN1, Sema ÖZTÜRK YILDIRIM2, Mustafa SOFİKERİM3, Erkan GÖCEN1
1Kayseri Eğitim ve Araştırma Hastanesi Radyasyon Onkoloji KAYSERİ
2Erciyes Üniversitesi Fen Fakültesi Fizik Bölümü KAYSERİ
3Acıbadem Üniversitesi Tıp Fakültesi Üroloji Bölümü KAYSERİ
Introduction: The aim is to find out whether a hypothetical diagnostic benefit exists in the assessment of trace elements in the hair of bladder cancer patients by comparing the results with healthy.

Materials and Method: In this prospective study, trace element analysis from patients with T1 bladder cancer (Group 1) and healthy (Group 2) was performed and their correlations were studied.

Results: The trace elements determined in the order of higher levels were Sn, Ca, Cu, Zn and Mg in Group 1 and Zn, Ca, Mg, Cu and Sn in Group 2. When the levels of trace elements were compared between groups As, Bi, Ca, Co, Cs, Cr, Fe, Ga, Hg, K, Li, Rh, Sb, Sn and V levels were found to be statistically different (p<0.05). According to Pearson correlation, powerful correlations were found for B, Be, Ce, Co, Cs, Cu, Hg, K, Ni, Pb, Rb, Se, Sn, V and Zn element in group; for Cs, Cr, Ga, Hg, Mn, Pb, Rh, Sr and Zn in Group 2.

Conclusion: This study demonstrated that heavy metal levels were higher in bladder cancer than in healthy. Our findings suggest that the heavy metals accumulated in the body may have an influence in bladder cancer development. Keywords : Bladder Cancer; Trace Elements; Inductively Coupled Plasma Mass Spectrometry; Scalp Hair